Assistant Professor · University of Copenhagen

Hengguan Huang

I build Bayesian AI systems that actively discover hidden mechanisms from incomplete and evolving evidence.

I lead the Scientific AI Group at the University of Copenhagen. My group develops Bayesian and agentic learning methods for mechanism discovery, reliable inference, and high-stakes biological and public-health systems.

01 Research

Three connected directions

One research agenda: discover mechanisms, seek the right evidence, and adapt without losing trust.

01

Mechanistic Bayesian Deep Learning

LERD framework connecting EEG signals, latent event dynamics, and an event relational graph.
Figure from LERD · ICML 2026

Learn explicit latent mechanisms—events, graphs, and dynamics—that explain how observations are generated.

I develop Bayesian deep models that recover structured latent mechanisms from incomplete observations, combining probabilistic graphs, continuous-time dynamics, and neural representations.

Representative work
LERD · ICML 2026 student-led · last author & lead corresponding author
iLoRA · ICML 2026 student-led · last author & lead corresponding author
02

Scientific Discovery Under Uncertainty

BayesAgent framework combining data, context, knowledge, a language model, and graphical model discovery.
Figure from BayesAgent · AAAI 2026

Build probabilistic and agentic systems that seek evidence, compare hypotheses, and revise beliefs under uncertainty.

I combine Bayesian inference, active evidence acquisition, and language-model reasoning to build scientific agents that know what to observe next, when to abstain, and how to update explanations.

Representative work
BayesAgent · AAAI 2026 first author & lead corresponding author
Bayesian Selective Latent Inference · 2026 student-led · lead corresponding author
03

Trustworthy & Safe AI for Health

A nested diffusion framework for reliable prediction from medical imaging under distribution shift.
Figure from Nested Diffusion · IEEE TMI 2025

Develop calibrated, fair, robust, and safe AI for high-stakes health systems under population and distribution shift.

I study uncertainty calibration, test-time adaptation, fairness, and generative modeling so clinical and public-health AI remains dependable as populations, modalities, and evidence change.

Representative work
02 Publications

Publication record

Full author lists are shown. Hengguan Huang is highlighted; * denotes equal contribution and † denotes corresponding author.

Showing 21 of 21 works

2026

Conference

iLoRA: Bayesian Low-Rank Adaptation with Latent Interaction Graphs for Microbiome Diagnosis

Yang Song, Yixuan Zhang, Lingfa Meng, Tongyuan Hu, Haizhou Shi, Hao Wang, Samir Bhatt, Hengguan Huang

International Conference on Machine Learning (ICML), 2026

Mechanistic AIBayesian LearningHealth AI
Conference

LERD: Latent Event-Relational Dynamics for Neurodegenerative Classification

Yicheng Feng*, Hairong Chen*, Ziyu Jia, Samir Bhatt, Hengguan Huang

International Conference on Machine Learning (ICML), 2026

Mechanistic AIBayesian LearningHealth AI
Conference

BayesAgent: Bayesian Agentic Reasoning Under Uncertainty via Verbalized Probabilistic Graphical Modeling

Hengguan Huang*, Xing Shen*, Guang-Yuan Hao, Songtao Wang, Lingfa Meng, Dianbo Liu, David Alejandro Duchene, Hao Wang, Samir Bhatt

AAAI Conference on Artificial Intelligence (AAAI), 2026

Scientific DiscoveryAgentic SystemsLLM Reasoning
Conference

Probabilistic Residual Learning for Online Recommendations

Wenyuan Wang*, Yusong Zhao*, Zihao Xu*, Hengyi Wang*, Qi Xu*, Zhigang Hua*, Yan Xie, Yi Wang, Zihao Zhao, Bo Long, Chengzhi Mao, Shuang Yang, Hengguan Huang, Hao Wang

20th ACM Conference on Recommender Systems (RecSys), 2026

Bayesian LearningRecommendationCausal Inference
Preprint

Bayesian Selective Latent Inference for Wastewater-First Influenza Monitoring

Yixuan Zhang, Yang Song, Hao Wang, Samir Bhatt, Hengguan Huang

arXiv preprint, 2026

Scientific DiscoveryActive Evidence AcquisitionHealth AI

2025

Journal

Improving Robustness and Reliability in Medical Image Classification with Latent-Guided Diffusion and Nested-Ensembles

Xing Shen, Hengguan Huang, Brennan Nichyporuk, Tal Arbel

IEEE Transactions on Medical Imaging, 44(12), 4890–4902, 2025

Reliable AIHealth AIGenerative Models
Conference

Exposing and Mitigating Calibration Biases and Demographic Unfairness in MLLM Few-Shot In-Context Learning for Medical Image Classification

Xing Shen, Justin Szeto, Mingyang Li, Hengguan Huang, Tal Arbel

Medical Image Computing and Computer Assisted Intervention (MICCAI), 2025

Health AIReliable AIMultimodal LLMs
Conference

On Calibration of LLM-based Guard Models for Reliable Content Moderation

Hongfu Liu, Hengguan Huang, Xiangming Gu, Hao Wang, Ye Wang

International Conference on Learning Representations (ICLR), 2025

Reliable AILanguage & SpeechLLM Safety

2024

Conference

Advancing Test-Time Adaptation in Wild Acoustic Test Settings

Hongfu Liu, Hengguan Huang, Ye Wang

Conference on Empirical Methods in Natural Language Processing (EMNLP), 2024

Reliable AILanguage & SpeechTest-time Adaptation
Conference

Benchmarking Large Language Models on Communicative Medical Coaching: A Novel System and Dataset

Hengguan Huang*, Songtao Wang*, Hongfu Liu, Hao Wang, Ye Wang

Findings of the Association for Computational Linguistics (ACL), 2024

Health AILanguage & SpeechLLM Evaluation

2023

ConferenceOral presentation

FedNP: Towards Non-IID Federated Learning via Federated Neural Propagation

Xueyang Wu*, Hengguan Huang*, Youlong Ding, Hao Wang, Ye Wang, Qian Xu

AAAI Conference on Artificial Intelligence (AAAI), 2023

Bayesian LearningFederated LearningGraph Learning
ThesisPhD Thesis Award — Honorable Mention

Brain-Informed Artificial Intelligence: Random Graphs, Dynamical Systems and Beyond

Hengguan Huang

PhD Thesis, National University of Singapore, 2023

Mechanistic AIBayesian Learning

2022

Conference

Extrapolative Continuous-time Bayesian Neural Network for Fast Training-free Test-time Adaptation

Hengguan Huang, Xiangming Gu, Hao Wang, Chang Xiao, Hongfu Liu, Ye Wang

Advances in Neural Information Processing Systems (NeurIPS), 2022

Reliable AIBayesian LearningTest-time Adaptation
Journal

Unsupervised Mismatch Localization in Cross-Modal Sequential Data with Application to Mispronunciations Localization

Wei Wei*, Hengguan Huang*, Xiangming Gu, Hao Wang, Ye Wang

Transactions on Machine Learning Research (TMLR), 2022

Language & SpeechBayesian LearningSequence Models
Preprint

EP-GAN: Unsupervised Federated Learning with Expectation-Propagation Prior GAN

Xueyang Wu, Hengguan Huang, Hao Wang, Ye Wang, Qian Xu

OpenReview preprint, 2022

Bayesian LearningFederated LearningGenerative Models

2021

Conference

STRODE: Stochastic Boundary Ordinary Differential Equation

Hengguan Huang, Hongfu Liu, Hao Wang, Chang Xiao, Ye Wang

International Conference on Machine Learning (ICML), 2021

Mechanistic AIBayesian LearningEvent Dynamics

2020

Conference

Deep Graph Random Process for Relational-Thinking-Based Speech Recognition

Hengguan Huang, Fuzhao Xue, Hao Wang, Ye Wang

International Conference on Machine Learning (ICML), 2020

Mechanistic AILanguage & SpeechGraph Learning

2019

ConferenceSpotlight presentation

Recurrent Poisson Process Unit for Speech Recognition

Hengguan Huang, Hao Wang, Brian Mak

AAAI Conference on Artificial Intelligence (AAAI), 2019

Bayesian LearningLanguage & SpeechSequence Models

2018

ConferenceOral presentation

WaveNet MH-SRU: Deep and Wide Multiple-History Simple Recurrent Unit for Speech Recognition

Hengguan Huang, Brian Mak

IEEE International Symposium on Chinese Spoken Language Processing (ISCSLP), 2018

Language & SpeechReliable AISequence Models

2017

Conference

To Improve the Robustness of LSTM-RNN Acoustic Models Using Higher-Order Feedback from Multiple Histories

Hengguan Huang, Brian Mak

Interspeech, 2017

Language & SpeechReliable AISequence Models

2015

Conference

An Investigation of Augmenting Speaker Representations to Improve Speaker Normalization for DNN-Based Speech Recognition

Hengguan Huang, Khe Chai Sim

IEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP), 2015

Language & SpeechRepresentation Learning
03 Service

Academic service & mentorship

Contributing to the research community through editorial work, peer review, student supervision, and sustained research mentoring.

01

Leadership

Community roles

  • Area Chair — ICLR 2027
  • Session Co-Chair — AAAI 2026, Reasoning under Uncertainty
  • Guest Editor — Big Data and Cognitive Computing
02

Peer review

Conference & journal service

  • ICML · NeurIPS · ICLR · AAAI · IJCAI
  • ACL Rolling Review · CVPR · ICCV · ICASSP
  • IEEE Transactions on Multimedia
03

Supervision

Current supervision

  • 2 PhD researchers (co-supervised) and 7 MSc students.
  • Student-led outcomes: iLoRA and LERD, ICML 2026; ongoing work in Bayesian scientific discovery.
04

Mentorship

Research mentoring

  • Past mentoring and collaboration across Bayesian learning, trustworthy AI, and scientific discovery.
04 Awards

Selected honors

Recognition for research and scholarship, with selection scale shown wherever it is verifiable.

2024

OpenAI Researcher Access Program

Quarterly reviewed
Selected grant recipient · four review cycles per year

2023/24

PhD Thesis Award, Honorable Mention

4 / 493 · 0.8%
Four honorable mentions among 493 NUS School of Computing students

2023

Selected poster presenter, Global Young Scientists Summit

60 / 1,300+ · ≈4.6%
Sixty presenters among more than 1,300 summit participants worldwide

2021/22

Dean’s Research Excellence Award

3 / 428 · 0.7%
Three recipients among 428 NUS School of Computing students

2019, 2023

Research Achievement Award

2× recipient
National University of Singapore · awarded in 2019 and 2023

2019, 2023

AAAI Student Scholarship

2× scholar
Limited conference travel-support program · awarded in 2019 and 2023

2022

NeurIPS Scholar Award

Main-track authors only
Funding-limited selection with seven-night attendance support
05 Contact

Let’s build scientific AI that earns trust.

Primary email

hengguan.huang@sund.ku.dk

Affiliation

University of Copenhagen
Øster Farimagsgade 5
1353 Copenhagen K, Denmark